in vitro stressor related changes in ovarian steroidogenesis



Saura Sahu C. Toxicology and Epigenetics Saura Sahu C. Toxicology and Epigenetics Новинка

Saura Sahu C. Toxicology and Epigenetics

16366.29 руб. Найти похожее
Epigenetics is the study of both heritable and non-heritable changes in the regulation of gene activity and expression that occur without an alteration in the DNA sequence. This dynamic and rapidly developing discipline is making its impact across the biomedical sciences, in particular in toxicology where epigenetic differences can mean that different individuals respond differently to the same drug or chemical. Toxicology and Epigenetics reflects the multidimensional character of this emerging area of toxicology, describing cutting-edge molecular technologies to unravel epigenetic changes, the use of in vivo and in vitro models, as well as the potential use of toxicological epigenetics in regulatory environments. An international team of experts consider the interplay between epigenetics and toxicology in a number of areas, including environmental, nutritional, pharmacological, and computational toxicology, nanomaterials, proteomics and metabolomics, and cancer research. Topics covered include: environment, epigenetics and diseases DNA methylation and toxicogenomics chromatin at the intersection of disease and therapy epigenomic actions of environmental arsenicals environment, epigenetics and cardiovascular health toxicology, epigenetics and autoimmunity ocular epigenomics: potential sites of environmental impact in development and disease nuclear RNA silencing and related phenomena in animals epigenomics – impact for drug safety sciences methods of global epigenomic profiling transcriptomics: applications in epigenetic toxicology Toxicology and Epigenetics is an essential insight into the current trends and future directions of research in this rapidly expanding field for investigators, toxicologists, risk assessors and regulators in academia, industry and government.
Park Kinam Oral Controlled Release Formulation Design and Drug Delivery. Theory to Practice Park Kinam Oral Controlled Release Formulation Design and Drug Delivery. Theory to Practice Новинка

Park Kinam Oral Controlled Release Formulation Design and Drug Delivery. Theory to Practice

This book describes the theories, applications, and challenges for different oral controlled release formulations. This book differs from most in its focus on oral controlled release formulation design and process development. It also covers the related areas like preformulation, biopharmaceutics, in vitro-in vivo correlations (IVIVC), quality by design (QbD), and regulatory issues.
Gaynor Bussell PCOS For Dummies Gaynor Bussell PCOS For Dummies Новинка

Gaynor Bussell PCOS For Dummies

Practical advice and information for living with Polycystic Ovarian Syndrome Polycystic Ovary Syndrome (PCOS) is a condition in which there is an imbalance of a woman's female sex hormones, and affects an estimated 10% of all women. This hormone imbalance may cause changes in the menstrual cycle, acne, small cysts in the ovaries, difficulty conceiving, high blood pressure, and other problems. It is treatable, but not curable, and sufferers have to rely on themselves for the long-term management of their condition. If you're living with PCOS, this guide gives you the latest information concerning treatments and research into Polycystic Ovarian Syndrome. PCOS For Dummies gives you a practical, plain-English guide to living with and managing Polycystic Ovarian Syndrome. In addition to providing valuable information concerning the causes and symptoms of Polycystic Ovarian Syndrome, PCOS For Dummies gives you the facts about the various treatment options that are available, including both traditional medical treatments and alternative therapies. Discusses the causes and symptoms of PCOS Advice for dealing with this disorder Covers the treatments and medicine available in the United States PCOS For Dummies is an invaluable resource for the millions who are suffering from this condition.
Franklin Keara Temperature and Plant Development Franklin Keara Temperature and Plant Development Новинка

Franklin Keara Temperature and Plant Development

14053.23 руб. Найти похожее
Plants are incredibly sensitive to changes in temperature. Changes of a single degree or two in ambient temperature can impact plant architecture, developmental processes, immune response, and plant reproduction. Temperature and Plant Development thoroughly explores plant molecular responses to changes in temperature with aim to understanding how plants perceive, integrate, and respond to temperature signals. Temperature and Plant Development explores the diverse molecular responses that plants exhibit as they face changing temperatures. Temperature-related changes and adaptations to essential developmental processes, such as germination, flowering, and reproduction, are explored in detail. Chapters also explore the impact of temperature on plant immune responses and the impact of rising temperatures on global food security. A timely and important book, Temperature and Plant Development will be a valuable resource for plant biologists, crop scientists, and advanced students. • Up-to-date and comprehensive coverage of the role of temperature on plant development. • Looks at changes and adaptations to plant developmental processes made in response to changing temperatures. • Explores the role of temperature on plant immune response and pathogen defense • Provides a timely look at the impact of changing temperatures on global food security
Stock Jay T. Human Bioarchaeology of the Transition to Agriculture Stock Jay T. Human Bioarchaeology of the Transition to Agriculture Новинка

Stock Jay T. Human Bioarchaeology of the Transition to Agriculture

A holistic and comprehensive account of the nature of the transition from hunting to farming in prehistory. It addresses for the first time the main bioarchaeological aspects such as changes in mobility, behaviour, diet and population dynamics. This book is of major interest to the relevant audience since it offers for the first time a global perspective on the bioarchaeology of the transition to agriculture. It includes contributions from world-class researchers, with a particular emphasis on advances in methods (e.g. ancient DNA of pathogens, stable isotope analysis, etc.). The book specifically addresses the following aspects associated with the transition to agriculture in various world regions: Changes in adult and subadult stature and subadult growth profiles Diachronic trends in the analysis of functional morphological structures (craniofacial, vault, lower limbs, etc.) and whether these are associated with change in overall sex-specific morphological variability Changes in mobility Changes in behaviour which can be reconstructed from the study of the skeletal record. These include changes in activity patterns, sexual dimorphism, evidence of inter-personal trauma, and the like. Population dynamics and microevolution by examining intra and inter population variations in dental and cranial metric traits, as well as archaeogenetic studies of ancient DNA (e.g. mtDNA markers).
Casazza Jack Understanding Electric Power Systems. An Overview of the Technology, the Marketplace, and Government Regulations Casazza Jack Understanding Electric Power Systems. An Overview of the Technology, the Marketplace, and Government Regulations Новинка

Casazza Jack Understanding Electric Power Systems. An Overview of the Technology, the Marketplace, and Government Regulations

Technological advances and changes in government policy and regulation have altered the electric power industry in recent years and will continue to impact it for quite some time. Fully updated with the latest changes to regulation, structure, and technology, this new edition of Understanding Electric Power Systems offers a real-world view of the industry, explaining how it operates, how it is structured, and how electricity is regulated and priced. It includes extensive references for the reader and will be especially useful to lawyers, government officials, regulators, engineers, and students, as well as the general public. The book explains the physical functioning of electric power systems, the electric power business in today's environment, and the related institutions, including recent changes in the roles of the Federal Energy Regulatory Commission and the North American Reliability Company. Significant changes that are affecting the industry are covered in this new edition, including: The expanded role of the federal government in the planning and operation of the nation's electric utilities New energy laws and a large number of FERC regulations implementing these laws Concerns over global warming and potential impacts on the electric industry Pressures for expansion of the electric grid and the implementation of «smart-grid» technologies The growing importance of various energy-storage technologies and renewable energy sources New nuclear generation technologies The 2009 economic stimulus package
Wu Ying Acid Gas Injection and Related Technologies Wu Ying Acid Gas Injection and Related Technologies Новинка

Wu Ying Acid Gas Injection and Related Technologies

15046.43 руб. Найти похожее
Large producers have started to use gas injection for their applications and in the future it is predicted that this trend will increase. This book is the most comprehensive and up-to-date coverage of this technique, which is rapidly increasing in importance and usage in the natural gas and petroleum industry. The authors, a group of the most well-known and respected in the field, discuss, in a series of papers, this technology and related technologies as to how they can best be used by industry to creating a safer, cleaner environment.
Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania Новинка

Managing Motherhood, Managing Risk : Fertility and Danger in West Central Tanzania

Book DescriptionAn investigation of the consequences resulting from fertility-related development interventions in Tanzania
Britain in Close-up: An In-Depth Study of Contemporary Britain Britain in Close-up: An In-Depth Study of Contemporary Britain Новинка

Britain in Close-up: An In-Depth Study of Contemporary Britain

This redesigned and updated edition of "Britain in Close-up" is an in-depth study of the public and private faces of contemporary Britain, and thoroughly examines the changes and challenges the nation faces as it enters the twenty-first century. "Britain in Close-up": comprehensively covers aspects of British society from government and politics to culture and style. has extensive activity material at the end of each chapter, complemented with charts, maps and graphs. incorporates Website lists for the latest access to related chapter information. uses a rich array of authentic texts conveniently highlighted in extract boxes. is illustrated throughout with attractive colour and black and white photographs. includes a wide range of bibliographic sources for further reading. Формат: 19,5 см x 26,5 см.
Metcalfe Sarah E. Quaternary Environmental Change in the Tropics Metcalfe Sarah E. Quaternary Environmental Change in the Tropics Новинка

Metcalfe Sarah E. Quaternary Environmental Change in the Tropics

The global climate changes that led to the expansion and contraction of high latitude ice sheets during the Quaternary period were associated with equally dramatic changes in tropical environments. These included shifts in vegetation zones, changes in the hydrology and ecology of lakes and rivers, and fluctuations in the size of mountain glaciers and sandy deserts. Until recently it was thought that such changes were triggered by fluctuations in the distribution of polar ice cover. Now there is increasing recognition that the tropics themselves have acted as drivers of global climate change over a range of timescales. The aim of Quaternary Environmental Change in the Tropics is to provide a synthesis of the changes that occurred in tropical terrestrial and marine systems during the Pleistocene and Holocene, complementing data-derived reconstructions with output from state-of-the-art climate models. It is targeted at final-year undergraduate students and research specialists, but will provide an introduction to tropical Quaternary research for a variety of other readers.
Matthew Asbell D. Intellectual Property Strategies for the 21st Century Corporation. A Shift in Strategic and Financial Management Matthew Asbell D. Intellectual Property Strategies for the 21st Century Corporation. A Shift in Strategic and Financial Management Новинка

Matthew Asbell D. Intellectual Property Strategies for the 21st Century Corporation. A Shift in Strategic and Financial Management

A practical approach to the modern management of intellectual property The world has changed significantly in the past decade, resulting in new behavior and practice related to the ownership and management of intellectual property. This book helps executives, attorneys, accountants, managers, owners, and others understand the legal, technological, economic, and cultural changes that have affected IP ownership and management. It provides case studies, practical examples and advice from seasoned and enduring professionals who have adopted new and streamlined methods and practices whether as in-house or outside counsel, or service providers. Provides a practical yet global approach to corporate IP management Serves as a resource for in-house and outside counsel, executives, managers, accountants, consultants and others at mid-size and large corporations Helps professionals navigate the numerous new challenges that have changed the ways in which intellectual property is obtained and managed Details the latest trends in valuation, exploitation, and protection of intellectual property Extensive coverage of the legal, financial, accounting and general business aspects of intellectual property The combined expertise of lawyers, accountants, economists and other business professionals Timely and relevant in view of the global economic recession amidst rampant technological development, this book offers new solutions, practices, policies and strategies as a result of changes in economies and markets, laws, globalization, environment, and public perception.
Mary McMurran Alcohol-Related Violence. Prevention and Treatment Mary McMurran Alcohol-Related Violence. Prevention and Treatment Новинка

Mary McMurran Alcohol-Related Violence. Prevention and Treatment

New in the Wiley Series in Forensic Clinical Psychology, Alcohol-Related Violence: Prevention and Treatment presents an authoritative collection of the most recent assessment and treatment strategies for alcohol-related aggression and violence. Features contributions from leading international academics and practitioners Offers invaluable guidance for practitioners regarding intervention to reduce alcohol-related aggression and violence Describes evidence-based interventions at a number of levels, including populations, bar room, families, couples, and individuals
Н. В. Кухарчик Размножение плодовых и ягодных растений в культуре in vitro Н. В. Кухарчик Размножение плодовых и ягодных растений в культуре in vitro Новинка

Н. В. Кухарчик Размножение плодовых и ягодных растений в культуре in vitro

В монографии обобщены результаты многолетних исследований по размножению в культуре in vitro сортов и подвоев плодовых и ягодных культур, выращиваемых в Беларуси. Изложены общие вопросы работ со стерильной культурой растений и особенности выращивания in vitro конкретных генотипов яблони, груши, вишни, сливы, смородины черной и красной, крыжовника, малины летней и ремонтантной, ежевики, земляники садовой, голубики, брусники, клюквы, рябины, аронии черноплодной. Предназначена для специалистов сельского хозяйства, преподавателей и студентов вузов.
Government Intervention in Sport Government Intervention in Sport Новинка

Government Intervention in Sport

This research focuses on a comparative analysis of government intervention on sporting facilities in the countries of Ireland and New Zealand. Both counties have rich sporting heritages with GAA dominating the sporting culture in Ireland and Rugby playing a similar role in New Zealand. These counties also have similar demographics and economies which make them suitable for a comparative analysis to be conducted. A large amount of finance has been invested in sport in Ireland over the last decade and this has seen some changes in the sporting infrastructure within the country. New Zealand has also invested heavily in the sport sector and the purpose of the comparative analysis will be to critically examine these changes and evaluate their success or failure.
Gerd Moller Geotechnik. Grundbau Gerd Moller Geotechnik. Grundbau Новинка

Gerd Moller Geotechnik. Grundbau

The book introduces in particular foundation methods and methods of securing level changes in terrain. The description of calculation and dimensioning with examples are a valuable orientation aid for those working in design and as technical experts.
Н. Кропачев,Валерий Мусин Russian Law in Brief: Digest for Foreign Investors Н. Кропачев,Валерий Мусин Russian Law in Brief: Digest for Foreign Investors Новинка

Н. Кропачев,Валерий Мусин Russian Law in Brief: Digest for Foreign Investors

The Edition provides foreigners with a comprehensive review of the Russian Legal System, court system, legisletive rules reffered to business with foreifn investors, encompasses the major changes and development in law, examines in detail renewed Russian legistation.
Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development Новинка

Urban Laszlo Predictive ADMET. Integrated Approaches in Drug Discovery and Development

10228.93 руб. Найти похожее
This book helps readers integrate in silico, in vitro, and in vivo ADMET (absorption, distribution, metabolism, elimination and toxicity) and PK (pharmacokinetics) data with routine testing applications so that pharmaceutical scientists can diagnose ADMET problems and present appropriate recommendations to move drug discovery programs forward. The book introduces the current clinical practice for drug discovery and development along with the impact on early risk assessment; consolidates the tools and models to intelligently integrate existing in silico, in vitro and in vivo ADMET data; and demonstrates successful cases and lessons learned from real drug discovery and development. In short, it is a book aimed to provide a practical road map for drug discovery and development scientists to generate efficacious and safe drugs for unmet medical needs.
Lourie Reichenberg W. DSM-5 Essentials. The Savvy Clinician's Guide to the Changes in Criteria Lourie Reichenberg W. DSM-5 Essentials. The Savvy Clinician's Guide to the Changes in Criteria Новинка

Lourie Reichenberg W. DSM-5 Essentials. The Savvy Clinician's Guide to the Changes in Criteria

Everything you need to know about the DSM-5 in an organized and concise presentation Providing you with a quick and easy way to get up-to-speed on recent changes to the two main classification systems—DSM-5 Essentials highlights these changes in a logical and systematic manner so that you can easily make the transition from DSM-IV to DSM-5. Author Lourie Reichenberg offers health care providers, instructors, clinicians in practice settings, and office staff who do coding for insurance reimbursement the information they need to do their jobs smoothly and efficiently with coverage of: The twenty classifications of disorders Emerging measures and models The future of diagnosis and treatment planning Matching clients' needs with the best evidence-based treatment Major changes to the DSM-5 such as the replacement of the multiaxial system, the developmental and lifespan approach, and cultural and gender considerations Arranged in the same sequence as the DSM-5, DSM-5 Essentials covers what has changed from the DSM-IV, what these changes mean for diagnosis, and the implication of these changes on the selection of effective, evidence-based treatment.
Alcamo Joseph Life in Europe Under Climate Change Alcamo Joseph Life in Europe Under Climate Change Новинка

Alcamo Joseph Life in Europe Under Climate Change

Life in Europe will indeed go on as the climate changes, but not in the same way as before. The air will be warmer, winds will change, patterns of rainfall and snowfall will alter, and sea level is likely to rise. These phenomena are already being seen. Europe will in the future experience marked changes in vegetation cover, increased floods along rivers and coastlines as well as more frequent droughts and forest fires, often leading to large societal costs. The changes will be minor in some cases, profound in others, but in any case, pervasive. This book uses the most up to date information issued by the IPCC (Intergovernmental Panel on Climate Change), and informs readers about these effects, as well as showing how Europe is contributing to attempts to slow the tempo of global climate change, and how it can adapt to the climate change that seems unavoidable. Life in Europe under Climate Change makes essential information on climate impacts in Europe accessible to a broad audience, including students, politicians, planners and members of non-governmental organizations.
Tom Leksey Locked-in Range Analysis: Why most traders must lose money in the futures market (Forex) Tom Leksey Locked-in Range Analysis: Why most traders must lose money in the futures market (Forex) Новинка

Tom Leksey Locked-in Range Analysis: Why most traders must lose money in the futures market (Forex)

The author is convinced that trading should be based on the reasons for price changes, otherwise it's Lucky-trading. The book describes the reasons for price changes of futures (Forex) and the new cause-and-effect method of analysis.
Rajput Nitendra Speech in Mobile and Pervasive Environments Rajput Nitendra Speech in Mobile and Pervasive Environments Новинка

Rajput Nitendra Speech in Mobile and Pervasive Environments

This book provides a cross-disciplinary reference to speech in mobile and pervasive environments Speech in Mobile and Pervasive Environments addresses the issues related to speech processing on resource-constrained mobile devices. These include speech recognition in noisy environments, specialised hardware for speech recognition and synthesis, the use of context to enhance recognition and user experience, and the emerging software standards required for interoperability. This book takes a multi-disciplinary look at these matters, while offering an insight into the opportunities and challenges of speech processing in mobile environs. In developing regions, speech-on-mobile is set to play a momentous role, socially and economically; the authors discuss how voice-based solutions and applications offer a compelling and natural solution in this setting. Key Features Provides a holistic overview of all speech technology related topics in the context of mobility Brings together the latest research in a logically connected way in a single volume Covers hardware, embedded recognition and synthesis, distributed speech recognition, software technologies, contextual interfaces Discusses multimodal dialogue systems and their evaluation Introduces speech in mobile and pervasive environments for developing regions This book provides a comprehensive overview for beginners and experts alike. It can be used as a textbook for advanced undergraduate and postgraduate students in electrical engineering and computer science. Students, practitioners or researchers in the areas of mobile computing, speech processing, voice applications, human-computer interfaces, and information and communication technologies will also find this reference insightful. For experts in the above domains, this book complements their strengths. In addition, the book will serve as a guide to practitioners working in telecom-related industries.
Methods in Enzymology: Volume 104: Enzyme Purification and Related Techniques: Part C Methods in Enzymology: Volume 104: Enzyme Purification and Related Techniques: Part C Новинка

Methods in Enzymology: Volume 104: Enzyme Purification and Related Techniques: Part C

The critically acclaimed laboratory standard, Methods in Enzymology, is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. The series contains much material still relevant today - truly an essential publication for researchers in all fields of life sciences.
Zed Rengel Improving Water and Nutrient-Use Efficiency in Food Production Systems Zed Rengel Improving Water and Nutrient-Use Efficiency in Food Production Systems Новинка

Zed Rengel Improving Water and Nutrient-Use Efficiency in Food Production Systems

14515.18 руб. Найти похожее
Improving Water and Nutrient Use Efficiency in Food Production Systems provides professionals, students, and policy makers with an in-depth view of various aspects of water and nutrient us in crop production. The book covers topics related to global economic, political, and social issues related to food production and distribution, describes various strategies and mechanisms that increase water and nutrient use efficiency, and review te curren situation and potential improvements in major food-producing systems on each continent. The book also deals with problems experienced by developed countries separtaely from problems facing developing countries. Improving Water and Nutrient Use Efficiency emphasizes judicious water and nutrient management which is aimed at maximising water and nutrient utilisation in the agricultural landscape, and minimising undesirable nutrient losses to the environment.
Игорь Борисов Партии на выборах Игорь Борисов Партии на выборах Новинка

Игорь Борисов Партии на выборах

Настоящая работа содержит сведения по вопросам, связанным с участием политических партий в выборах. В книге, изданной с учетом последних изменений федерального законодательства в июле 2007 года, содержатся ответы на практические вопросы, возникающие в правоприменительной практике. Настоящее издание адресовано широкому кругу читателей: юристам, политикам, политологам, активистам политических партий и всем, кто интересуется вопросами избирательного права и законодательством о партиях. The present work contains information on issues related to the political parties' participation in elections. The book takes into account all the latest changes to the federal laws that were introduced in June 2007 and also includes answers to practical questions that arise in law-enforcement practice. The present edition is meant for a wide circle of readers: legal practitioners, politicians, political scientists, political parties' activists and all those who are interested in the issues of electoral law and party legislation.
Hanrahan Grady Chemometric Methods in Capillary Electrophoresis Hanrahan Grady Chemometric Methods in Capillary Electrophoresis Новинка

Hanrahan Grady Chemometric Methods in Capillary Electrophoresis

Use chemometric techniques to develop optimum separation conditions for capillary electrophoreses For all its advantages, capillary electrophoresis (CE) also carries significant disadvantages for the researcher. Offering a unique blend of information from authors active in a variety of developments of chemometrics in CE, Chemometric Methods in Capillary Electrophoresis presents modern chemometric methods as an alternative to help alleviate the problems commonly encountered during routine analysis and method development. Focusing on current chemometric methods utilized in CE endeavours by research-active experts in the field, the book begins with a thorough introduction to CE and chemometric-related concepts and the need for modern chemometric methods in CE. Part 1 discusses differing types of screening designs and response surface methodology¿in an¿application based format Part 2 includes vital discussion on various exploratory data analysis, prediction, and classification techniques utilized in CE-related studies Part 3 provides practical information on modelling quantitative structure relationships Part 4 explores transformation techniques, in particular fundamental studies and applications of cross-correlation and Hadamard Transform Electrophoresis Showing how chemometric methods are applied in a wide array of applications including biological, medical, pharmaceutical, food, forensic, and environmental science, Chemometric Methods in Capillary Electrophoresis is not only highly significant to capillary electrophoresis-based endeavours, but instructive for investigators active in other areas of separation science who could benefit from its informative content.
Sedat Tardu Transport and Coherent Structures in Wall Turbulence Sedat Tardu Transport and Coherent Structures in Wall Turbulence Новинка

Sedat Tardu Transport and Coherent Structures in Wall Turbulence

13261.31 руб. Найти похожее
Wall bounded turbulent flows are of major importance in industrial and environmental fluid mechanics. The structure of the wall turbulence is intrinsically related to the coherent structures that play a fundamental role in the transport process. The comprehension of their regeneration mechanism is indispensable for the development of efficient strategies in terms of drag control and near wall turbulence management. This book provides an up-to-date overview on the progress made in this specific area in recent years.
Guomin Shan Immunoassays in Agricultural Biotechnology Guomin Shan Immunoassays in Agricultural Biotechnology Новинка

Guomin Shan Immunoassays in Agricultural Biotechnology

A very broad range of professionals are using immunoassay technology daily to analyze genetically engineered (GE) crops and related areas, and many of these professionals are completely new to this technology. There is a great need for users to have a book containing technical and practical guidance, and describing limitations and pitfalls of applying immunoassay in agricultural biotechnology. This book focuses on the application of immunoassays to GE plants and related areas. A group of international experts from government agencies, academics and industries, who have many years of related experience, contribute high quality chapters in their areas of expertise. This book covers topics including principles of immunoassay, antibody engineering in AgBiotech, current technologies (formats, kit development, manufacturing and quality control), method validation, applications in trait discovery and product development, applications in grain products and food processing, applications in environmental monitoring, automation and high throughput, reference materials, data interpretation and source of error, and future perspectives and challenges. In addition, to meet the practical needs for a variety of readers from different backgrounds, methods and protocols are included as well.
Paul Rosenberg Audel Guide to the 2011 National Electrical Code. All New Edition Paul Rosenberg Audel Guide to the 2011 National Electrical Code. All New Edition Новинка

Paul Rosenberg Audel Guide to the 2011 National Electrical Code. All New Edition

The NEC is updated every 3 years with some of the anticipated changes include new requirements to sections while some of the changes include entirely new articles. Some changes are revisions to existing requirements while others are deletions to some existing requirements. As with the last edition of this book the author will use an icon or other graphical feature to highlight all changes to the 2011 code from the 2008 version. The book is considered an easy reference tool for those individuals on the job in need of a handy reference without the bulk and formality of the code itself. Significant changes to wiring and protection sections as well as new coverae of hybrid electric vehicles and small wind turbine power generators are being made. As always there will be numerous small changes made throughout the book. In short if a change has been made to the code it will be covered in this book in an easy to read instructional way.
Raz Jelinek Lipids and Cellular Membranes in Amyloid Diseases Raz Jelinek Lipids and Cellular Membranes in Amyloid Diseases Новинка

Raz Jelinek Lipids and Cellular Membranes in Amyloid Diseases

13000.64 руб. Найти похожее
Addressing one of the biggest riddles in current molecular cell biology, this ground-breaking monograph builds the case for the crucial involvement of lipids and membranes in the formation of amyloid deposits. Tying together recent knowledge from in vitro and in vivo studes, and built on a sound biophysical and biochemical foundation, this overview brings the reader up to date with current models of the interplay between membranes and amyloid formation. Required reading for any researcher interested in amyloid formation and amyloid toxicity, and possible avenues for the prevention or treatment of neurodegenerative disorders. From the contents: * Interactions of Alpha-Synuclein with Lipids * Interaction of hIAPP and its Precursors with Membranes * Amyloid Polymorphisms: Structural Basis and Significance in Biology and Molecular Medicine * The Role of Lipid Rafts in Alzheimer's Disease * Alzheimer's Disease as a Membrane-Associated Enzymopathy of Beta-Amyloid Precursor Protein (APP) Secretases * Impaired Regulation of Glutamate Receptor Channels and Signaling Molecules by Beta-Amyloid in Alzheimer's Disease * Membrane Changes in BSE and Scrapie * Experimental Approaches and Technical Challenges for Studying Amyloid-Membrane Interactions and more
Jens-Uwe Peters Polypharmacology in Drug Discovery Jens-Uwe Peters Polypharmacology in Drug Discovery Новинка

Jens-Uwe Peters Polypharmacology in Drug Discovery

An essential outline of the main facets of polypharmacology in drug discovery research Extending drug discovery opportunities beyond the «one drug, one target» philosophy, a polypharmacological approach to the treatment of complex diseases is emerging as a hot topic in both industry and academic research. Polypharmacology in Drug Discovery presents an overview of the various facets of polypharmacology and how it can be applied as an innovative concept for developing medicines for treating bacterial infections, epilepsy, cancer, psychiatric disorders, and more. Filled with a collection of instructive case studies that reinforce the material and illuminate the subject, this practical guide: Covers the two-sided nature of polypharmacology—its contribution to adverse drug reactions and its benefit in certain therapeutic drug classes Addresses the important topic of polypharmacology in drug discovery, a subject that has not been thoroughly covered outside of scattered journal articles Overviews state-of-the-art approaches and developments to help readers understand concepts and issues related to polypharmacology Fosters interdisciplinary drug discovery research by embracing computational, synthetic, in vitro and in vivo pharmacological and clinical aspects of polypharmacology A clear road map for helping readers successfully navigate around the problems involved with promiscuous ligands and targets, Polypharmacology in Drug Discovery provides real examples, in-depth explanations and discussions, and detailed reviews and opinions to spark inspiration for new drug discovery projects.
Alexey Kavokin The Acronis Chronicles Alexey Kavokin The Acronis Chronicles Новинка

Alexey Kavokin The Acronis Chronicles

The Acronis Chronicles is an engaging fiction story about adventuresof a young girl named Acronis and her brother, a pilot in racingsports. In the book, Acronis encounters a mystery related to themisfortunes of her brother's racing teams. Her ambitious sleuthinghelps authorities capture an international criminal.
International Express: Intermediate: Student's CD International Express: Intermediate: Student's CD Новинка

International Express: Intermediate: Student's CD

Presents grammar through international contexts, for students to analyze and formulate the rules. This title focuses on English for socializing, telephoning, and participating in discussions, enabling learners to communicate confidently in work-related situations. It also includes a workbook, a student's cassette and an audio CD.
Richard Hogg M. A Grammar of Old English, Volume 1. Phonology Richard Hogg M. A Grammar of Old English, Volume 1. Phonology Новинка

Richard Hogg M. A Grammar of Old English, Volume 1. Phonology

First published in 1992, A Grammar of Old English, Volume 1: Phonology was a landmark publication that in the intervening years has not been surpassed in its depth of scholarship and usefulness to the field. With the 2011 posthumous publication of Richard M. Hogg’s Volume 2: Morphology, Volume 1 is again in print, now in paperback, so that scholars can own this complete work. Takes account of major developments both in the field of Old English studies and in linguistic theory Takes full advantage of the Dictionary of Old English project at Toronto, and includes full cross-references to the DOE data Fully utilizes work in phonemic and generative theory and related topics Provides material crucial for future research both in diachronic and synchronic phonology and in historical sociolinguistics
Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications Новинка

Tiwari Ashutosh Responsive Materials and Methods. State-of-the-Art Stimuli-Responsive Materials and Their Applications

15772.35 руб. Найти похожее
The development of finely-tuned materials that adjust in a predictable manner by specific environment change is the recent arena of materials research. It is a newly emerging supra-disciplinary field with huge commercial potential. Stimuli-responsive materials answer by a considerable change in their properties to small changes in their environment. Responsive materials are becoming increasingly more prevalent as scientists learn about the chemistry and triggers that induce conformational changes in materials structures and devise ways to take advantage of and control them. Responsive Materials and Method offers state-of-the-art of the stimuli-responsive materials and their potential applications. This collection brings together novel methodologies and strategies adopted in the research and development of responsive materials and technology.
Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology Новинка

Eric Toone J. Advances in Enzymology and Related Areas of Molecular Biology

This book covers important advances in enzymology, explaining the behavior of enzymes and how they can be utilized to develop novel drugs, synthesize known and novel compounds, and understand evolutionary processes.
Purich Daniel L. Advances in Enzymology and Related Areas of Molecular Biology Purich Daniel L. Advances in Enzymology and Related Areas of Molecular Biology Новинка

Purich Daniel L. Advances in Enzymology and Related Areas of Molecular Biology

10228.93 руб. Найти похожее
Encompasses the latest advances in the field. New series editor, Daniel Purich, is a well-known biochemist and enzymologist.
C. Gonzalez Alternative Methodologies for Social Assessment of Environmental Projects C. Gonzalez Alternative Methodologies for Social Assessment of Environmental Projects Новинка

C. Gonzalez Alternative Methodologies for Social Assessment of Environmental Projects

The main objective of this contribution is to propose different methodologies in order to find and compare new solutions for evaluating social projects. We have chosen two approaches: hedonic price and contingent valuation. These procedures can be presented in a quantitative and/or qualitative form. We emphasize the social assessment in terms of benefits of the related environmental projects.
Paul Pregosin S. NMR in Organometallic Chemistry Paul Pregosin S. NMR in Organometallic Chemistry Новинка

Paul Pregosin S. NMR in Organometallic Chemistry

The first and ultimate guide for anyone working in transition organometallic chemistry and related fields, providing the background and practical guidance on how to efficiently work with routine research problems in NMR. The book adopts a problem-solving approach with many examples taken from recent literature to show readers how to interpret the data. Perfect for PhD students, postdocs and other newcomers in organometallic and inorganic chemistry, as well as for organic chemists involved in transition metal catalysis.
Steven Kaplan M. Wiley's English-Spanish Spanish-English Chemistry Dictionary Steven Kaplan M. Wiley's English-Spanish Spanish-English Chemistry Dictionary Новинка

Steven Kaplan M. Wiley's English-Spanish Spanish-English Chemistry Dictionary

This Dictionary provides over 75,000 entries covering all areas of chemistry, such as Chemical Biology, Biochemistry, Biotechnology, and Nanochemistry, plus relevant terms in related spheres of expertise. In order to prepare this Second Edition, the First Edition was completely revised, and over 35,000 new terms were added. This new edition will continue to be the Dictionary that chemists, educators, students, translators, and those working in English and Spanish in chemistry and associated fields have been trusting since the First Edition was published in 1998.
Bob Dylan In America Bob Dylan In America Новинка

Bob Dylan In America

Growing up in Greenwich Village in the 1960s Sean Wilentz discovered the music of Bob Dylan as a young teenager. Almost half a century later, now a distinguished professor of American history, he revisits Dylan's work with the critical skills of a scholar and the passion of a fan. Drawing partly on his work as the current historian-in-residence on Dylan's official website, Sean Wilentz provides a unique blend of biography, memoir and anlysis in a book which, much like its subject, shifts gears and changes shape as the occasion demands.
Elena Kotyrlo Space-time dynamics of fertility and commuting Elena Kotyrlo Space-time dynamics of fertility and commuting Новинка

Elena Kotyrlo Space-time dynamics of fertility and commuting

The study contributes in analytical description of spatial diffusion of fertility, in particular, influenced by labour movements of people between places of residence and work. It is assumed that the labour market has externality on the marriage market due to commuting, which, in turn, affects fertility. A model of spatial diffusion of fertility is based on assumption of global and local spillover effects. The global spillover effect, as shifts in fertility norms, is motivated by increasing variance of social interactions of an individual, when places of work and residence are different. One local spillover effect is in response to flows of earnings across space. Another mechanism is related to expected changes in probabilities to find a partner affected by differences in day and night population. The analytical model, in which the effects on fertility of the cited spillovers are decomposed, is constructed in the paper on the base of a model of the demand for children, spatial stock-flow model of a market, and a matching model with a sex imbalance or spatial mismatch as the probability of matching. Three sex imbalances, namely of night-, day-time population and an adjusted to sex imbalance of commuters to residents are empirically tested. Empirical evidence on municipal Swedish data for the period 1994–2008 does not provide any strong evidence of spatial diffusion of fertility. However, there are externalities of labour mobility on fertility due to changes of gender structure of population.
Lee Mike S. Dried Blood Spots. Applications and Techniques Lee Mike S. Dried Blood Spots. Applications and Techniques Новинка

Lee Mike S. Dried Blood Spots. Applications and Techniques

An informative and comprehensive book on the applications and techniques of dried blood spot sampling Dried blood spot (DBS) sampling involves the collection of a small volume of blood, via a simple prick or other means, from a study subject onto a cellulose or polymer paper card, which is followed by drying and transfer to the laboratory for analysis. For many years, this method of blood sample collection has been extensively utilized in some important areas of human healthcare (for example, newborn screening for inherited metabolic disorders and HIV-related epidemiological studies). Because of its advantages over conventional blood, plasma, or serum sample collection, DBS sampling has been valued by the pharmaceutical industry in drug research and development. Dried Blood Spots: Applications and Techniques features contributions from an international team of leading scientists in the field. Their contributions present a unique resource on the history, principles, procedures, methodologies, applications, and emerging technologies related to DBS. Presented in three parts, the book thoroughly examines: Applications of DBS sampling and associated procedures and methodologies in various human healthcare studies Applications and perspectives of DBS sampling in drug research and development, and therapeutic drug monitoring New technologies and emerging applications related to DBS sampling and analysis Dried Blood Spots: Applications and Techniques is a valuable working guide for researchers, professionals, and students in healthcare, medical science, diagnostics, clinical chemistry, and pharmaceuticals, etc.
Ranjan Patnaik Engineering Complex Phenotypes in Industrial Strains Ranjan Patnaik Engineering Complex Phenotypes in Industrial Strains Новинка

Ranjan Patnaik Engineering Complex Phenotypes in Industrial Strains

This book highlights current trends and developments in the area of engineering strains. The book details the current and future tools used in the production of bulk chemicals and biofuels from renewable biomass using green technologies. Complex phenotypes are traits in a microbe that requires multiple genetic changes to be modulated simultaneously in the microorganism’s DNA. Knowing what those genetic changes are for a given trait and how to make those changes in the most efficient way forms the motivation behind writing this book. This book explains the newer tools to develop and enable engineered strains at time scales much faster that the natural evolution process so that we can increase a cells' production of a certain substance, increase process productivity, and extend metabolic capability. This book provides a one stop platform of reference for practicing researchers in the field of industrial biotechnology. This book also explains that the commercial success of a process that uses microbial catalysts over platforms that use chemical catalysts and fossil fuels depends on the time it takes to engineer these microbes to perform the desired reaction under harsh manufacturing conditions and at rates that meets the criteria for economic feasibility.
Ю. Е. Демидчик Эффект мезенхимальных стволовых клеток при клеточной терапии рассеянного склероза Ю. Е. Демидчик Эффект мезенхимальных стволовых клеток при клеточной терапии рассеянного склероза Новинка

Ю. Е. Демидчик Эффект мезенхимальных стволовых клеток при клеточной терапии рассеянного склероза

В монографии представлен методологический подход к in vitro и in vivo оценке иммуномодулирующих свойств мезенхимальных стволовых клеток при использовании клеточных культур для иммунотерапии рассеянного склероза. Предназначена для специалистов в области клеточных технологий, иммунологов, нейроиммунологов, неврологов, трансплантологов, биологов.
Dale Jeremy W. Molecular Genetics of Bacteria Dale Jeremy W. Molecular Genetics of Bacteria Новинка

Dale Jeremy W. Molecular Genetics of Bacteria

The fifth edition of this highly successful book provides students with an essential introduction to the molecular genetics of bacteria covering the basic concepts and the latest developments. It is comprehensive, easy to use and well structured with clear two-colour diagrams throughout. Specific changes to the new edition include: More detail on sigma factors, anti-sigma factors and anti-anti sigma factors, and the difference in the frequency of sigma factors in bacteria Expand material on integrons as these are becoming increasingly important in antibiotic resistance Enhanced treatment of molecular phylogeny Complete revision and updating of the final chapter on ‘Gene Mapping and Genomics’ Two-colour illustrations throughout. The focus of the book remains firmly on bacteria and will be invaluable to students studying microbiology, biotechnology, molecular biology, biochemistry, genetics and related biomedical sciences.
Sophia Dziegielewski F. DSM-5 in Action Sophia Dziegielewski F. DSM-5 in Action Новинка

Sophia Dziegielewski F. DSM-5 in Action

Full exploitation of the DSM-5 allows for more comprehensive care By demystifying the DSM-5, author Sophia Dziegielewski goes beyond the traditional diagnostic assessment and suggests both treatment plans and practice strategy. She covers the changes in criteria to the DSM-5 and what those changes mean for mental health professionals. This resource has been updated to include: New and updated treatment plans All treatment plans, interventions strategies, applications, and practice implications are evidence based Instructions on doing diagnostic assessments and differential diagnosis using the DSM-5 Changes to coding and billing using the DSM-5 and ICD-10 The book includes robust tools for students, instructors, and new graduates seeking licensure. DSM-5 in Action makes the DSM-5 accessible to all practitioners, allowing for more accurate, comprehensive care.
Ted Shelton Business Models for the Social Mobile Cloud. Transform Your Business Using Social Media, Mobile Internet, and Cloud Computing Ted Shelton Business Models for the Social Mobile Cloud. Transform Your Business Using Social Media, Mobile Internet, and Cloud Computing Новинка

Ted Shelton Business Models for the Social Mobile Cloud. Transform Your Business Using Social Media, Mobile Internet, and Cloud Computing

Fully exploit new conditions and opportunities created by current technological changes The combined impact of social technologies, the mobile Internet, and cloud computing are creating incredible new business opportunities. They are also destroying unprepared companies, transforming industries, and leaving behind workers who are unwilling or unable to adapt. Business Models for the Social Mobile Cloud reveals a compelling view from PwC of how the social mobile cloud and a combination of new technology changes are key players in a digital transformation in business and society that is moving more quickly and cutting more deeply than any technology transformation ever seen. Explores a road map to success through adapting to technological changes Written for businesses and leaders who want to understand how the coming technology changes will eventually impact their businesses For companies to succeed, leaders must understand how to stay ahead of their competitors in adapting to the new conditions and opportunities. In Business Models for the Social Mobile Cloud, PwC’s Ted Shelton describes the tectonic changes currently underway—and to come—plus why they are happening, what to expect, and what you must do about.
Phillips Gary J. Biomimetic, Bioresponsive, and Bioactive Materials. An Introduction to Integrating Materials with Tissues Phillips Gary J. Biomimetic, Bioresponsive, and Bioactive Materials. An Introduction to Integrating Materials with Tissues Новинка

Phillips Gary J. Biomimetic, Bioresponsive, and Bioactive Materials. An Introduction to Integrating Materials with Tissues

The accessible introduction to biomaterials and their applications in tissue replacement, medical devices, and more Molecular and cell biology is being increasingly integrated into the search for high-performance biomaterials and biomedical devices, transforming a formerly engineering- and materials science–based field into a truly interdisciplinary area of investigation. Biomimetic, Bioresponsive, and Bioactive Materials presents a comprehensive introduction to biomaterials, discussing how they are selected, designed, and modified for integration with living tissue and how they can be utilized in the development of medical devices, orthopedics, and other related areas. Examining the physico chemical properties of widely used biomaterials and their uses in different clinical fields, the book explores applications including soft and hard tissue replacement; biointeractive metals, polymers, and ceramics; and in vitro, in vivo, and ex vivo biocompatibility tests and clinical trials. The book critically assesses the clinical level of research in the field, not only presenting proven research, but also positing new avenues of exploration. Biomimetic, Bioresponsive, and Bioactive Materials contains everything needed to get a firm grasp on materials science, fast. Written in an accessible style and including practice questions that test comprehension of the material covered in each chapter, the book is an invaluable tool for students as well as professionals new to the field.
Mike Morris Concise Dictionary of Social and Cultural Anthropology Mike Morris Concise Dictionary of Social and Cultural Anthropology Новинка

Mike Morris Concise Dictionary of Social and Cultural Anthropology

Practical and accessible, this dictionary is designed to enlighten those newly engaged in anthropological study or seeking a quick guide to the field. Fills a need for a beginner’s pocket guide to the far-reaching and complex field of anthropology, including over 800 detailed entries and the intellectual background of terms Written in plain, jargon-free language, for readers without extensive background in the field Features brief, conceptual definitions of terms, bibliographical references to anthropological classics, related works for background reading and further research The user-friendly format includes bold terms featured elsewhere in the book, extensive cross-references, and indexes of names, peoples, places and subjects Incorporates related terminology from allied fields such as sociology, economics and geography
David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing Новинка

David J. am Ende Chemical Engineering in the Pharmaceutical Industry. R&D to Manufacturing

15109.12 руб. Найти похожее
This book deals with various unique elements in the drug development process within chemical engineering science and pharmaceutical R&D. The book is intended to be used as a professional reference and potentially as a text book reference in pharmaceutical engineering and pharmaceutical sciences. Many of the experimental methods related to pharmaceutical process development are learned on the job. This book is intended to provide many of those important concepts that R&D Engineers and manufacturing Engineers should know and be familiar if they are going to be successful in the Pharmaceutical Industry. These include basic analytics for quantitation of reaction components– often skipped in ChE Reaction Engineering and kinetics books. In addition Chemical Engineering in the Pharmaceutical Industry introduces contemporary methods of data analysis for kinetic modeling and extends these concepts into Quality by Design strategies for regulatory filings. For the current professionals, in-silico process modeling tools that streamline experimental screening approaches is also new and presented here. Continuous flow processing, although mainstream for ChE, is unique in this context given the range of scales and the complex economics associated with transforming existing batch-plant capacity. The book will be split into four distinct yet related parts. These parts will address the fundamentals of analytical techniques for engineers, thermodynamic modeling, and finally provides an appendix with common engineering tools and examples of their applications.
Otto Wildi Data Analysis in Vegetation Ecology Otto Wildi Data Analysis in Vegetation Ecology Новинка

Otto Wildi Data Analysis in Vegetation Ecology

Evolving from years of teaching experience by one of the top experts in vegetation ecology, Data Analysis in Vegetation Ecology aims to explain the background and basics of mathematical (mainly multivariate) analysis of vegetation data. The book lays out the basic operations involved in the analysis, the underlying hypotheses, aims and points of views. It conveys the message that each step in the calculations has a specific, straightforward meaning and that patterns and processes known by ecologists often find their counterpart in mathematical operations and functions. The first chapters introduce the elementary concepts and operations and relate them to real-world phenomena and problems. Later chapters concentrate on combinations of methods to reveal surprising features in data sets. Showing how to find patterns in time series, how to generate simple dynamic models, how to reveal spatial patterns and related occurrence probability maps.
Отсутствует Биотехнология в селекции растений. Клеточная инженерия Отсутствует Биотехнология в селекции растений. Клеточная инженерия Новинка

Отсутствует Биотехнология в селекции растений. Клеточная инженерия

В третьем томе отражены результаты исследований по генетике морфогенеза in vitro у таких культур, как пшеница, томат, лен, ячмень и тритикале. Генетические исследования явления гаплоидии представлены работами по пшенице, томату, тритикале, картофелю, сахарной свекле. Освещены вопросы соматической гибридизации и селекции in vitro у картофеля. Отдельная глава представлена анализом данных по размножению in vitro плодовых и ягодных культур. Рассматривается использование методов гаметной селекции у самоопылителей – томата и люпина. Значительное место отведено результатам работы по клональному микроразмножению растений. В отдельной главе отражены результаты использования биотехнологических методов у лесных культур. Монография рассчитана на научных работников в области генетики и селекции растений, преподавателей и студентов биологических и сельскохозяйственных вузов, специалистов сельского хозяйства.
Elder Ken Phase-Field Methods in Materials Science and Engineering Elder Ken Phase-Field Methods in Materials Science and Engineering Новинка

Elder Ken Phase-Field Methods in Materials Science and Engineering

This comprehensive and self-contained, one-stop source discusses phase-field methodology in a fundamental way, explaining advanced numerical techniques for solving phase-field and related continuum-field models. It also presents numerical techniques used to simulate various phenomena in a detailed, step-by-step way, such that readers can carry out their own code developments. Features many examples of how the methods explained can be used in materials science and engineering applications.

кешбака
Страницы:


This book provides a cross-disciplinary reference to speech in mobile and pervasive environments Speech in Mobile and Pervasive Environments addresses the issues related to speech processing on resource-constrained mobile devices. These include speech recognition in noisy environments, specialised hardware for speech recognition and synthesis, the use of context to enhance recognition and user experience, and the emerging software standards required for interoperability. This book takes a multi-disciplinary look at these matters, while offering an insight into the opportunities and challenges of speech processing in mobile environs. In developing regions, speech-on-mobile is set to play a momentous role, socially and economically; the authors discuss how voice-based solutions and applications offer a compelling and natural solution in this setting. Key Features Provides a holistic overview of all speech technology related topics in the context of mobility Brings together the latest research in a logically connected way in a single volume Covers hardware, embedded recognition and synthesis, distributed speech recognition, software technologies, contextual interfaces Discusses multimodal dialogue systems and their evaluation Introduces speech in mobile and pervasive environments for developing regions This book provides a comprehensive overview for beginners and experts alike. It can be used as a textbook for advanced undergraduate and postgraduate students in electrical engineering and computer science. Students, practitioners or researchers in the areas of mobile computing, speech processing, voice applications, human-computer interfaces, and information and communication technologies will also find this reference insightful. For experts in the above domains, this book complements their strengths. In addition, the book will serve as a guide to practitioners working in telecom-related industries.
Продажа in vitro stressor related changes in ovarian steroidogenesis лучших цены всего мира
Посредством этого сайта магазина - каталога товаров мы очень легко осуществляем продажу in vitro stressor related changes in ovarian steroidogenesis у одного из интернет-магазинов проверенных фирм. Определитесь с вашими предпочтениями один интернет-магазин, с лучшей ценой продукта. Прочитав рекомендации по продаже in vitro stressor related changes in ovarian steroidogenesis легко охарактеризовать производителя как превосходную и доступную фирму.